SMITH genomics lab
Department of Pharmaceutical Sciences and Experimental Therapeutics
The Smith genomics lab merges the disciplines of genetics, neuroscience, and pharmacology to identify promising new drug treatments and biomarkers for brain-related disorders.
Pharmacogenomics
USING GENETICS TO PREDICT DRUG RESPONSE
Systematic, pragmatic, and rigorous approach to identify genetic variants that influcence pharmacokinetic and pharmacodynamic responses to drugs.
Synaptic Genomics
UNDERSTANDING TEMPORAL AND SPATIAL RNA DYNAMICS
Using an array of genomic tools, we seek to understand the factors that determine which RNA molecules reach the synapse and how they are regulated in response to plasticity.
New Drug Target Identification
GENETIC VALIDATION OF NOVEL TARGETS
Finding new ways to leverage the power of human genetics to identify and validate new drug targets that have increased probability of clinical success.